Synthesis and DNA cleavage activity of a bifunctional intercalator-linked copper(II) macrocycle.
نویسندگان
چکیده
An intercalator-linked macrocycle 3,6-bis(dimethylamino)-10-(6-[1,4,7-triazacyclononane]hexyl) acridinium bromide was synthesized, its copper(ii) complex was prepared, and the DNA cleavage activity of this metal complex was compared to that of the intercalator-free (Cu[9]aneN(3))(2+) complex.
منابع مشابه
Ultrastable complexes for in vivo use: a bifunctional chelator incorporating a cross-bridged macrocycle.
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ورودعنوان ژورنال:
- Chemical communications
دوره 46 شماره
صفحات -
تاریخ انتشار 2008